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Crispr Gene-Drive Technologies For Urban Population Engineering
Víctor López Del Amo
, Brittany S. Leger
, Kurt J. Cox
, Shubhroz Gill
, Alena L. Bishop
, Garrett D. Scanlon
, James A. Walker
, Valentino M. Gantz
and Amit Choudhary
|
Full Paper
|
2022
By surpassing the 50% inheritance limit of Mendel’s law of gene segregation, CRISPR-based gene drives have the potential to fight urban vector-borne diseases or suppress urban pests, but contemporary gene drives can spread unchecked and lack an analog output that modulates inheritance between 50–100...