Isocycloseram: An Innovative Compound For Cockroach Control

A cockroach bait containing 1% isocycloseram demonstrated a high level of effectiveness against a broad spectrum of economically relevant cockroach species (American, German, Brown-Banded, Oriental and Turkestan cockroaches) in a series of laboratory arena trials with different cockroach densities. At application rates spanning from 0.5 g of bait to 2.0 g of bait per m² over 90% control was achieved between 10 and 14 days after exposure. Furthermore, research conducted by Lee (2021) showed isocycloseram's effectiveness against resistant German cockroach strains. Complete control of adults and nymphs in four out of five tested strains resistant to multiple conventional insecticides was achieved, with 96.7% mortality in the fifth strain, underscoring isocycloseram's potential in combating insecticide resistance. The gradual onset of isocycloseram's biological activity enables effective population control through horizontal transfer among conspecifics. After removing the adults and bait, ten first instar nymphs were introduced, resulting in 100% mortality within four days of exposure to the primary donors' excretions.