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SURVIVAL ANALYSIS for the DETECTION of LOW-LEVEL INSECTICIDE RESISTANCE

Author(s): Glenn Holbrook, Ken Berger, Annie Steed and Don Lesiewicz
Year: 2002
Keywords: blattella germanica fipronil logistic regression resistance ratios cox regression hazard ratios
Abstract:
This study compares statistical methodologies for the detection of low levels of insecticide resistance in the German cockroach. Results show that logistic regression and resistance ratios are relatively ineffective in distinguishing modest differences between strains, whether dose-mortality or time-mortality data are obtained. An improved method involves proportional hazards modeling, known as Cox regression. This method distinguished small differences in fipronil tolerance between a field collected and an insecticide- susceptible strain.
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