Report 
  Title  
  Impact of Insecticide Resistance on Control of Aedes Aegypti
  Key Words  
  Insecticide resistance
  Author  
  Maria De Lourdes Da Graça Macoris, Maria Teresa M. Andrighetti and Paulo Eduardo Martins Ribolla
  Abstract  
  The biological characterization of resistance in laboratory is reported, along with an evaluation of the response of vector populations to methods of chemical control which are used on the routine executed in the Dengue Control .Data from the Monitoring Program demonstrated over time an increasing number of resistant populations to the main larvicide used (temephos), that adult resistance to the pyrethroid class is spread across the state since 2000 and that there is a decreased field control in resistant populations. There is evidence that the development of insecticide resistance has been influenced by intensive control of epidemics since this was more pronounced in populations of Aedes aegypti from the regions with the highest cumulative incidence of the disease. We conclude that there is a general trend of loss of susceptibility to products used for the control of Aedes aegypti. The management strategies were not enough, so far, to reverse resistance. Control actions in the field were less effective in populations characterized as “Resistant” in laboratory evaluation, indicating that resistance management must be adopted when insect populations are in the “reduced susceptibility” status. The use of insecticides is a self-limited tool that must be preserved and dengue control should be based on more sustainable strategies.